CKDdb-logoCKDdb - Molecule ID A5973

geneCAPN2, CANPL2
nameCalpain-2 catalytic subunit
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAN2_HUMANP17655ENSG00000162909824Hs.350899114230

Functions and classifications

GOC:chromatin, C:cytoplasm, C:dendrite, C:nucleus, C:plasma membrane, F:calcium ion binding, F:calcium-dependent cysteine-type endopeptidase activity, P:blastocyst development, P:cellular response to amino acid stimulus, P:myoblast fusion, P:protein autoprocessing, P:proteolysis, P:response to hypoxia, C:intracellular, F:cysteine-type peptidase activity
UniProt3D-structure, Acetylation, Alternative splicing, Calcium, Cell membrane, Complete proteome, Cytoplasm, Direct protein sequencing, Hydrolase, Membrane, Metal-binding, Polymorphism, Protease, Reference proteome, Repeat, Thiol protease
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.263.26E-08RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.010.00000124RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.17< 0.05RNA microarray21752957
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.496.15E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium