CKDdb-logoCKDdb - Molecule ID A5971

geneCAPN12
nameCalpain 12
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAN12_HUMANQ6ZSI9ENSG00000182472147968Hs.731775608839

Functions and classifications

GOC:intracellular, F:calcium ion binding, F:calcium-dependent cysteine-type endopeptidase activity, P:proteolysis
UniProtCalcium, Complete proteome, Hydrolase, Metal-binding, Polymorphism, Protease, Reference proteome, Thiol protease
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)10.761.99E-05RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)10.590.005776RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium