CKDdb-logoCKDdb - Molecule ID A5970

geneCAPN11
nameCalpain 11
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAN11_HUMANQ9UMQ6ENSG0000013722511131Hs.225953604822

Functions and classifications

GOC:acrosomal vesicle, F:calcium ion binding, F:calcium-dependent cysteine-type endopeptidase activity, P:proteolysis, C:intracellular
UniProtCalcium, Complete proteome, Cytoplasmic vesicle, Hydrolase, Metal-binding, Polymorphism, Protease, Reference proteome, Repeat, Thiol protease
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.0191RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.31.24E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.170.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium