CKDdb-logoCKDdb - Molecule ID A596F

geneCAPN10
nameCalpain-10
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAN10_HUMANQ9HC96ENSG0000014233011132Hs.728234601283, 605286

Functions and classifications

GOC:cytosol, C:plasma membrane, F:calcium-dependent cysteine-type endopeptidase activity, F:cytoskeletal protein binding, F:SNARE binding, P:actin cytoskeleton reorganization, P:cellular response to insulin stimulus, P:execution phase of apoptosis, P:positive regulation of glucose import, P:positive regulation of insulin secretion, P:positive regulation of intracellular transport, P:positive regulation of type B pancreatic cell apoptotic process, P:proteolysis, P:type B pancreatic cell apoptotic process, C:intracellular, P:positive regulation of apoptotic process
UniProtAlternative splicing, Complete proteome, Diabetes mellitus, Hydrolase, Polymorphism, Protease, Reference proteome, Repeat, Thiol protease
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.410.0108187RNA microarray19698090
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)3.40.0070799RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium