CKDdb-logoCKDdb - Molecule ID A5965

geneCA3
nameCarbonic anhydrase 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAH3_HUMANP07451ENSG00000164879761Hs.82129114750

Functions and classifications

GOC:cytosol, F:carbonate dehydratase activity, F:nickel cation binding, F:zinc ion binding, P:bicarbonate transport, P:one-carbon metabolic process, P:response to ethanol, P:response to oxidative stress, P:small molecule metabolic process, C:cytoplasm, P:metabolic process, F:metal ion binding
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Glutathionylation, Lyase, Metal-binding, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)5.250.05RNA microarray17579666
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)0.43< 0.05LC-MS/MS19845401
Exp21183621Homo sapiens24bloodserumChronic_Renal_Insufficiency (Chronic kidney disease)2.70.0023ProtoArray human protein microarray V3, (Invitrogen, PAH052401)21183621
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.440cDNA microarray21411733
Exp23326503Rattus norvegicus kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)2.160.00021639mRNA microarray23326503
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)4.680.0420272RNA microarray23935909
Exp24761003bRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.49< 0.05LC-MS/MS24761003
Exp24761003cRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.45< 0.05LC-MS/MS24761003

Compile date 08-10-2018© iMODE-CKD consortium