CKDdb-logoCKDdb - Molecule ID A5960

geneCA12
nameCarbonic anhydrase 12
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAH12_HUMANO43570ENSG00000074410771Hs.210995143860, 603263

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:carbonate dehydratase activity, F:zinc ion binding, P:bicarbonate transport, P:one-carbon metabolic process, P:small molecule metabolic process, C:integral to membrane, F:metal ion binding
UniProt3D-structure, Alternative splicing, Complete proteome, Disease mutation, Disulfide bond, Glycoprotein, Lyase, Membrane, Metal-binding, Reference proteome, Signal, Transmembrane, Transmembrane helix, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.170.0000299RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.240.000178RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.000143RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.260.000477RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.30.00464RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.0179RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.371.98E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.381.50E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.381.50E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.415.80E-05RNA microarray20019191
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.570.000486783RNA microarray20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp21544065bRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)1.620.026MALDI-TOF/TOF21544065
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.30.0382699RNA microarray23935909
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium