CKDdb-logoCKDdb - Molecule ID A5959

geneCA1
nameCarbonic anhydrase 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAH1_HUMANP00915ENSG00000133742759Hs.23118114800

Functions and classifications

GOC:cytosol, C:Golgi apparatus, F:carbonate dehydratase activity, F:zinc ion binding, P:bicarbonate transport, P:one-carbon metabolic process, P:small molecule metabolic process, C:cytoplasm, F:metal ion binding
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Lyase, Metal-binding, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp17242005Homo sapiens27urinewholeGlomerulonephritis (IgA nephropathy)3.3 LC-MS/MS 17242005
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.00265RNA microarray 19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.210.0387RNA microarray 19698090
Exp20007950aRattus norvegicus8corporawholeDiabetes (Diabetes Mellitus-associated Erectile Dysfunction)1.720.031MALDI-TOF, LC-MS/MS 20007950
Exp20007950bRattus norvegicus8corporawholeDiabetes (Diabetes Mellitus-associated Erectile Dysfunction)1.170.031MALDI-TOF, LC-MS/MS 20007950
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)0.760.0087QSTAR Elite LC-MS/MS 22172726
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)3.210.00003LC-MS/MS 23228063
Exp25619383Homo sapiens46bloodplasmaFabry (Fabry) 0.02LC-MS/MSMRM25619383
Exp25666440Homo sapiens23urinesupernatantFabry (naive Fabry patients)2.330.019143nanoLC-ESI-MS/MS 25666440

Compile date 08-10-2018© iMODE-CKD consortium