CKDdb-logoCKDdb - Molecule ID A5952

geneC1RL, C1RL1, C1RLP
nameComplement C1r-like proteinase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
C1RL_HUMANQ9NZP8ENSG0000013917851279Hs.631730608974

Functions and classifications

GOC:extracellular space, F:serine-type endopeptidase activity, P:complement activation, classical pathway, P:innate immune response, P:proteolysis, P:proteolysis
UniProtComplement pathway, Complete proteome, Disulfide bond, Glycoprotein, Hydrolase, Immunity, Innate immunity, Polymorphism, Protease, Reference proteome, Secreted, Serine protease, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.370.00000313RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)5.44< 0.05RNA microarray21752957
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)0.740hybrid quadrupole-TOF, LC-MS/MS22536212
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.590.00003LC-MS/MS23228063
Exp24096133aHomo sapiens10urine>10kDaDiabetes (type 1 diabetes without retinopathy or nephropathy)2.25 1DE, MALDI24096133
Exp24096133bHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy)0 1DE, MALDI24096133
Exp24096133cHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy)4.75 1DE, MALDI24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)0 1DE, MALDI24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy)2.11 1DE, MALDI24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy)1000 1DE, MALDI24096133
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome)2.27.30E-03LC-MS25150443
Exp25279147Homo sapiens12kidneybiopsy sectionGlomerulonephritis (IgA nephropathy)2.58< 0.05MALDI TOF/TOF25279147
Exp25667632Homo sapiens10kidneybiopsy sectionGlomerulonephritis (membranous nephropathy)2.36< 0.05MALDI-TOF/TOF25667632
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.270.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium