CKDdb-logoCKDdb - Molecule ID A5944

geneBRSK2, PEN11B, SADA
nameSerine/threonine-protein kinase 29
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BRSK2_HUMANQ8IWQ3ENSG000001746729024Hs.170819609236

Functions and classifications

GOC:centrosome, C:cytoplasm, C:endoplasmic reticulum, C:perinuclear region of cytoplasm, F:ATP binding, F:magnesium ion binding, F:protein serine/threonine kinase activity, F:tau-protein kinase activity, P:actin cytoskeleton reorganization, P:axonogenesis, P:establishment of cell polarity, P:exocytosis, P:G2/M transition of mitotic cell cycle, P:intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress, P:mitosis, P:peptidyl-serine phosphorylation, P:regulation of insulin secretion involved in cellular response to glucose stimulus, P:protein phosphorylation, F:kinase activity, P:cell division
UniProtAlternative splicing, Apoptosis, ATP-binding, Cell cycle, Cell division, Complete proteome, Cytoplasm, Cytoskeleton, Endoplasmic reticulum, Exocytosis, Kinase, Magnesium, Metal-binding, Mitosis, Neurogenesis, Nucleotide-binding, Phosphoprotein, Reference proteome, Serine/threonine-protein kinase, Transferase, Ubl conjugation
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.290.0063RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.343.18E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium