CKDdb-logoCKDdb - Molecule ID A5933

geneBMP1, PCOLC
nameBone morphogenetic protein 1 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BMP1_HUMANP13497ENSG00000168487649Hs.1274112264, 614856

Functions and classifications

GOC:extracellular region, C:extracellular space, C:Golgi apparatus, C:membrane-bounded vesicle, C:proteinaceous extracellular matrix, F:calcium ion binding, F:metalloendopeptidase activity, F:zinc ion binding, P:cartilage condensation, P:cell differentiation, P:extracellular matrix organization, P:lipoprotein metabolic process, P:ossification, P:positive regulation of cartilage development, P:proteolysis, P:small molecule metabolic process, C:collagen, P:lipid metabolic process, F:metal ion binding
UniProt3D-structure, Alternative splicing, Calcium, Chondrogenesis, Cleavage on pair of basic residues, Complete proteome, Cytokine, Developmental protein, Differentiation, Disease mutation, Disulfide bond, EGF-like domain, Extracellular matrix, Glycoprotein, Golgi apparatus, Growth factor, Hydrolase, Metal-binding, Metalloprotease, Osteogenesis, Osteogenesis imperfecta, Polymorphism, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen, Collagen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.30.00161RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.000026RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.450.000663RNA microarray19698090
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.32< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium