CKDdb-logoCKDdb - Molecule ID A5931

geneBLK
nameTyrosine-protein kinase BLK
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BLK_HUMANP51451ENSG00000136573640Hs.146591191305, 613375

Functions and classifications

GOC:plasma membrane, F:ATP binding, F:non-membrane spanning protein tyrosine kinase activity, P:B cell receptor signaling pathway, P:intracellular signal transduction, P:positive regulation of insulin secretion, F:protein tyrosine kinase activity, P:peptidyl-tyrosine phosphorylation, P:intracellular protein kinase cascade, F:protein kinase activity
UniProtATP-binding, Cell membrane, Complete proteome, Diabetes mellitus, Kinase, Lipoprotein, Membrane, Myristate, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, SH2 domain, SH3 domain, Transferase, Tyrosine-protein kinase, Ubl conjugation
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.470.0362633RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.190.00000549RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.240.000672RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium