CKDdb-logoCKDdb - Molecule ID A5928

geneBLVRA, BLVR, BVR
nameBiliverdin reductase A precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BIEA_HUMANP53004ENSG00000106605644Hs.488143109750, 614156

Functions and classifications

GOC:cytosol, F:biliverdin reductase activity, F:zinc ion binding, P:heme catabolic process, P:small molecule metabolic process, F:oxidoreductase activity, P:oxidation-reduction process, F:metal ion binding, F:nucleotide binding
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Metal-binding, NAD, NADP, Oxidoreductase, Phosphoprotein, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)2.250.0183151RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.0243RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)11.791.57E-09RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.540.000000302RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.962.31E-08RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.993.23E-06RNA microarray20019191
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.160.000016RNA microarray23291264
Exp23291264bRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.340.0267RNA microarray23291264
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)2.19 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.48< 0.05RNA-seq23757392
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.90.033344771LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.484.30E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium