CKDdb-logoCKDdb - Molecule ID A5926

geneBhmt
nameBetaine--homocysteine S-methyltransferase 1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BHMT1_MOUSEO35490ENSMUSG0000006932412116Mm.329582602888

Functions and classifications

GOC:cytoplasm, F:betaine-homocysteine S-methyltransferase activity, F:S-adenosylmethionine-homocysteine S-methyltransferase activity, F:zinc ion binding, P:amino-acid betaine catabolic process, P:methionine biosynthetic process, F:homocysteine S-methyltransferase activity, F:metal ion binding
UniProtComplete proteome, Cytoplasm, Metal-binding, Methyltransferase, Reference proteome, Transferase, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.268.24E-06RNA microarray20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)4.090.006cDNA microarray21411733
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)2.640.024MALDI-TOF/TOF21544065
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)1.120.0031QSTAR Elite LC-MS/MS22172726
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.550.00003LC-MS/MS23228063
Exp24172336Mus musculus6kidneycortexAKI (AKI)3.260.02133305LC-MS/MS24172336
Exp24211404Homo sapiens16urineexosomeDiabetes (diabetic nephropathy)0.290.00035LC-MS/MS24211404

Compile date 08-10-2018© iMODE-CKD consortium