CKDdb-logoCKDdb - Molecule ID A5922

geneBckdk
name[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCKD_MOUSEO55028ENSMUSG0000003080212041Mm.425495614901, 614923

Functions and classifications

GOC:mitochondrial alpha-ketoglutarate dehydrogenase complex, C:mitochondrion, F:[3-methyl-2-oxobutanoate dehydrogenase (acetyl-transferring)] kinase activity, F:ATP binding, F:protein kinase activity, F:protein serine/threonine kinase activity, P:branched-chain amino acid catabolic process, P:phosphorylation, P:protein phosphorylation, C:mitochondrial alpha-ketoglutarate dehydrogenase complex, C:mitochondrion, F:ATP binding, F:protein kinase activity, F:protein serine/threonine kinase activity, P:protein phosphorylation, C:mitochondrion, F:ATP binding, F:protein kinase activity, P:protein phosphorylation
UniProtAcetylation, ATP-binding, Complete proteome, Kinase, Mitochondrion, Nucleotide-binding, Phosphoprotein, Reference proteome, Serine/threonine-protein kinase, Transferase, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.30.00000111RNA microarray24569379
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)5.160.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium