CKDdb-logoCKDdb - Molecule ID A5921

geneBco2, Bcdo2
nameBeta,beta-carotene 9',10'-oxygenase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCDO2_MOUSEQ99NF1ENSMUSG00000032066170752Mm.390149611740

Functions and classifications

GOC:intracellular, C:mitochondrion, F:metal ion binding, F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen, P:carotene catabolic process, P:carotene metabolic process, P:carotenoid metabolic process, P:oxidation-reduction process, P:regulation of mitochondrial membrane potential, P:regulation of reactive oxygen species metabolic process, P:retinal metabolic process, P:retinoic acid metabolic process, F:dioxygenase activity
UniProtComplete proteome, Dioxygenase, Iron, Metal-binding, Mitochondrion, Oxidoreductase, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.25< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)2.99< 0.05RNA-seq23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.370.000183RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium