CKDdb-logoCKDdb - Molecule ID A5920

geneBCAT2, BCATM, BCT2
nameBranched-chain amino acid aminotransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCAT2_HUMANO15382ENSG00000105552587Hs.512670113530

Functions and classifications

GOC:mitochondrial matrix, F:branched-chain-amino-acid transaminase activity, F:L-isoleucine transaminase activity, F:L-leucine transaminase activity, F:L-valine transaminase activity, P:branched-chain amino acid biosynthetic process, P:branched-chain amino acid catabolic process, P:cellular nitrogen compound metabolic process, P:isoleucine catabolic process, P:leucine metabolic process, P:regulation of hormone levels, P:valine metabolic process, C:mitochondrion, C:nucleus, P:lactation, P:leucine biosynthetic process, P:isoleucine biosynthetic process, P:valine biosynthetic process
UniProt3D-structure, Acetylation, Alternative splicing, Amino-acid biosynthesis, Aminotransferase, Branched-chain amino acid biosynthesis, Complete proteome, Cytoplasm, Mitochondrion, Polymorphism, Pyridoxal phosphate, Reference proteome, Transferase, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)6.45< 0.05cDNA microarrays17183245
Exp18850734Canis lupus familiaris kidneydistal renal tubular cellskidney_calculi (Calcium oxalate monohydrate in vitro model)1.50.016Q-TOF MS/MS18850734
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.00336RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium