CKDdb-logoCKDdb - Molecule ID A5919

geneBcat1, Eca39
nameBranched-chain-amino-acid aminotransferase, cytosolic
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BCAT1_MOUSEP24288ENSMUSG0000003026812035Mm.4606113520

Functions and classifications

GOC:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, F:L-isoleucine transaminase activity, F:L-leucine transaminase activity, F:L-valine transaminase activity, P:branched-chain amino acid biosynthetic process, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, F:L-isoleucine transaminase activity, F:L-leucine transaminase activity, F:L-valine transaminase activity, P:branched-chain amino acid biosynthetic process, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, F:L-isoleucine transaminase activity, F:L-leucine transaminase activity, F:L-valine transaminase activity, P:branched-chain amino acid biosynthetic process, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, F:L-isoleucine transaminase activity, F:L-leucine transaminase activity, F:L-valine transaminase activity, P:branched-chain amino acid biosynthetic process, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint, , C:cytosol, C:mitochondrion, F:branched-chain-amino-acid transaminase activity, P:branched-chain amino acid catabolic process, P:cellular response to UV, P:mitotic G1 DNA damage checkpoint
UniProtAcetylation, Amino-acid biosynthesis, Aminotransferase, Branched-chain amino acid biosynthesis, Complete proteome, Cytoplasm, Pyridoxal phosphate, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.160.000113RNA microarray24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.336.58E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.150.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium