CKDdb-logoCKDdb - Molecule ID A5918

geneAcot7, Bach
nameCytosolic acyl coenzyme A thioester hydrolase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BACH_MOUSEQ91V12ENSMUSG0000002893770025Mm.296191602587

Functions and classifications

GOC:cell body, C:cytosol, C:neuron projection, F:palmitoyl-CoA hydrolase activity, P:fatty acid catabolic process, F:carboxylesterase activity
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Hydrolase, Reference proteome, Repeat, Serine esterase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.546.38E-06RNA microarray20019191
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.50.002cDNA microarray21411733
Exp24172336Mus musculus6kidneycortexAKI (AKI)4.190.00236776LC-MS/MS24172336
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)19.250.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium