CKDdb-logoCKDdb - Molecule ID A5918

geneAcot7, Bach
nameCytosolic acyl coenzyme A thioester hydrolase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BACH_MOUSEQ91V12ENSMUSG0000002893770025Mm.296191602587

Functions and classifications

GOC:cell body, C:cytosol, C:neuron projection, F:palmitoyl-CoA hydrolase activity, P:fatty acid catabolic process, F:carboxylesterase activity
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Hydrolase, Reference proteome, Repeat, Serine esterase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis) 1.546.38E-06RNA microarray  20019191
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis) 0.50.002cDNA microarray  21411733
Exp24172336Mus musculus6kidneycortexAKI (AKI) 4.190.00236776LC-MS/MS  24172336
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 19.250.013999RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium