CKDdb-logoCKDdb - Molecule ID A5900

geneB3GNT1, B3GNT6
nameN-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
B3GN1_HUMANO43505ENSG0000017468411041Hs.8526605517, 615287

Functions and classifications

GOC:integral component of Golgi membrane, F:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity, P:axon guidance, P:keratan sulfate biosynthetic process, P:poly-N-acetyllactosamine biosynthetic process, P:protein glycosylation, F:N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity, C:integral to Golgi membrane
UniProtComplete proteome, Congenital muscular dystrophy, Disease mutation, Dystroglycanopathy, Glycoprotein, Glycosyltransferase, Golgi apparatus, Lissencephaly, Membrane, Polymorphism, Reference proteome, Signal-anchor, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20847290Homo sapiens30kidneyglomeruliGlomerulonephritis (FSGS + COLL)0.510.0842RNA microarray20847290
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.21< 0.05RNA microarray21752957
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.520.0032LC-MS/MS23228063
Exp24189015aHomo sapiens5bloodmononuclear cellshealthy (healthy)3.52 +/- 0.51< 0.001RNA microarray24189015
Exp24189015bHomo sapiens9bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)3.59 +/- 0.69< 0.001RNA microarray24189015
Exp24189015cHomo sapiens10bloodmononuclear cellsDialysis (Peritoneal dialysis)2.56 +/- 0.89< 0.001RNA microarray24189015
Exp24189015dHomo sapiens17bloodmononuclear cellsDialysis (hemodialysis)2.57 +/- 0.79< 0.001RNA microarray24189015

Compile date 08-10-2018© iMODE-CKD consortium