CKDdb-logoCKDdb - Molecule ID A5888

geneADAMTS8, METH2
nameADAMTS-8 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATS8_HUMANQ9UP79ENSG0000013491711095Hs.271605605175

Functions and classifications

GOC:proteinaceous extracellular matrix, F:heparin binding, F:integrin binding, F:low affinity phosphate transmembrane transporter activity, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:negative regulation of cell proliferation, P:proteolysis, P:metabolic process, C:extracellular matrix, F:metal ion binding
UniProtCleavage on pair of basic residues, Complete proteome, Disulfide bond, Extracellular matrix, Glycoprotein, Heparin-binding, Hydrolase, Metal-binding, Metalloprotease, Protease, Reference proteome, Repeat, Secreted, Signal, Zinc, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.260.0052RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium