CKDdb-logoCKDdb - Molecule ID A5875

geneATP9A, ATPIIA
namePotential phospholipid-transporting ATPase IIA
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATP9A_HUMANO75110ENSP0000034248110079Hs.649234609126

Functions and classifications

GOC:early endosome, C:early endosome membrane, C:Golgi apparatus, C:integral component of membrane, C:perinuclear region of cytoplasm, C:recycling endosome, C:trans-Golgi network, F:ATP binding, F:cation-transporting ATPase activity, F:magnesium ion binding, F:phospholipid-translocating ATPase activity, P:ATP catabolic process, P:ion transmembrane transport, P:phospholipid translocation, C:early endosome, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport, P:phospholipid translocation, C:integral to membrane, P:cation transport
UniProtAcetylation, Alternative splicing, ATP-binding, Complete proteome, Endosome, Golgi apparatus, Hydrolase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Reference proteome, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.76< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.18< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium