CKDdb-logoCKDdb - Molecule ID A5870

geneATL1, SPG3A, GBP3
nameAtlastin
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATLA1_HUMANQ8WXF7ENSG0000019851351062Hs.584905182600, 606439, 613708

Functions and classifications

GOC:axon, C:endoplasmic reticulum membrane, C:Golgi cis cisterna, C:Golgi membrane, C:integral component of membrane, F:GTP binding, F:GTPase activity, F:identical protein binding, P:axonogenesis, P:cell death, P:endoplasmic reticulum organization, P:protein homooligomerization, P:GTP catabolic process, C:integral to membrane
UniProt3D-structure, Alternative splicing, Cell projection, Coiled coil, Complete proteome, Disease mutation, Endoplasmic reticulum, Golgi apparatus, GTP-binding, Hereditary spastic paraplegia, Hydrolase, Membrane, Neurodegeneration, Neuropathy, Nucleotide-binding, Phosphoprotein, Reference proteome, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.486.57E-05RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium