CKDdb-logoCKDdb - Molecule ID A5869

geneATG7, APG7L, GSA7
nameAutophagy-related protein 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATG7_HUMANO95352ENSP0000034643710533Hs.38032608760

Functions and classifications

GOC:axoneme, C:pre-autophagosomal structure, F:APG12 activating enzyme activity, F:protein homodimerization activity, F:ubiquitin activating enzyme activity, P:adult walking behavior, P:autophagy, P:cardiac muscle cell development, P:cellular amino acid metabolic process, P:central nervous system neuron axonogenesis, P:cerebellar Purkinje cell layer development, P:cerebral cortex development, P:liver development, P:membrane fusion, P:negative regulation of apoptotic process, P:neurological system process, P:organelle organization, P:positive regulation of macroautophagy, P:positive regulation of protein modification process, P:post-embryonic development, P:protein catabolic process, P:protein lipidation, P:protein modification by small protein conjugation, P:protein transport, P:pyramidal neuron development, P:regulation of protein ubiquitination, P:response to starvation, C:cytoplasm, F:catalytic activity, F:nucleotide binding, P:cellular membrane fusion, P:metabolic process, P:cellular membrane organization
UniProtAcetylation, Alternative splicing, Autophagy, Complete proteome, Cytoplasm, Polymorphism, Protein transport, Reference proteome, Transport, Ubl conjugation pathway
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21183621Homo sapiens24bloodserumChronic_Renal_Insufficiency (Chronic kidney disease)4.80.0001ProtoArray human protein microarray V3, (Invitrogen, PAH052401)21183621

Compile date 08-10-2018© iMODE-CKD consortium