CKDdb-logoCKDdb - Molecule ID A5868

geneATG3, APG3, APG3L
nameAutophagy-related protein 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ATG3_HUMANQ9NT62ENSG0000014484864422Hs.477126609606

Functions and classifications

GOC:cytoplasmic ubiquitin ligase complex, C:cytosol, F:Atg12 ligase activity, F:Atg8 ligase activity, P:autophagic vacuole assembly, P:mitochondrial fragmentation involved in apoptotic process, P:protein targeting to membrane, P:protein ubiquitination, P:regulation of cilium assembly
UniProt3D-structure, Acetylation, Alternative splicing, Autophagy, Complete proteome, Cytoplasm, Isopeptide bond, Ligase, Protein transport, Reference proteome, Transport, Ubl conjugation, Ubl conjugation pathway
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.151.57E-08RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.913.23E-06RNA microarray20019191

Compile date 08-10-2018© iMODE-CKD consortium