CKDdb-logoCKDdb - Molecule ID A5858

geneATP8A2, ATPIB
namePotential phospholipid-transporting ATPase IB
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT8A2_HUMANQ9NTI2ENSG0000013293251761Hs.444957605870, 615268

Functions and classifications

GOC:integral component of membrane, F:ATP binding, F:cation-transporting ATPase activity, F:magnesium ion binding, F:phospholipid-translocating ATPase activity, P:aging, P:ATP catabolic process, P:axonogenesis, P:eating behavior, P:involuntary skeletal muscle contraction, P:ion transmembrane transport, P:negative regulation of cell proliferation, P:neuromuscular process controlling posture, P:phospholipid translocation, P:positive regulation of multicellular organism growth, P:skin development, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport, P:negative regulation of cell proliferation, P:cation transport, C:integral to membrane
UniProtAlternative splicing, ATP-binding, Chromosomal rearrangement, Complete proteome, Disease mutation, Hydrolase, Magnesium, Membrane, Mental retardation, Metal-binding, Nucleotide-binding, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Phosphoprotein
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.290.00388RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.0317RNA microarray19698090
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.31< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium