CKDdb-logoCKDdb - Molecule ID A5847

geneATP11B
nameProbable phospholipid-transporting ATPase IF
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
E9Q0M7_MOUSEE9Q0M7ENSMUSG0000003740023200Mm.239416605869

Functions and classifications

GOC:early endosome, C:endoplasmic reticulum, C:integral component of membrane, C:nuclear inner membrane, C:plasma membrane, C:recycling endosome, C:recycling endosome membrane, F:ATP binding, F:cation-transporting ATPase activity, F:ion transmembrane transporter activity, F:magnesium ion binding, F:phospholipid-translocating ATPase activity, P:aminophospholipid transport, P:ATP catabolic process, P:phospholipid translocation, P:ion transmembrane transport, "C:early endosome, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport, P:phospholipid translocation", "C:integral to membrane, P:cation transport"
UniProtATP-binding, Complete proteome, Endoplasmic reticulum, Endosome, Hydrolase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Phosphoprotein, Reference proteome, Transmembrane, Transmembrane helix
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24172336Mus musculus6kidneycortexAKI (AKI)2.820.017620295LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.491.36E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium