CKDdb-logoCKDdb - Molecule ID A5846

geneATP11A, ATPIH, ATPIS
namePotential phospholipid-transporting ATPase IH
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AT11A_HUMANP98196ENSG0000006865023250Hs.29189605868

Functions and classifications

GOC:early endosome, C:endoplasmic reticulum, C:integral component of membrane, C:lysosomal membrane, C:plasma membrane, C:recycling endosome, F:ATP binding, F:cation-transporting ATPase activity, F:magnesium ion binding, F:phospholipid-translocating ATPase activity, P:ATP catabolic process, P:ion transmembrane transport, P:phospholipid translocation, C:early endosome, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport, P:phospholipid translocation, C:integral to membrane, P:cation transport
UniProtATP-binding, Cell membrane, Complete proteome, Endoplasmic reticulum, Endosome, Hydrolase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.22< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.22< 0.05cDNA microarray17003339
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.340.0458798RNA microarray23935909
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.950.043478913LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium