CKDdb-logoCKDdb - Molecule ID A5844

geneATP10B, ATPVB
namePotential phospholipid-transporting ATPase VB
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
AT10B_HUMANO94823ENSG0000011832223120Hs.109358

Functions and classifications

GOC:cytoplasmic vesicle membrane, C:endoplasmic reticulum, C:endoplasmic reticulum membrane, C:integral component of membrane, F:ATP binding, F:cation-transporting ATPase activity, F:magnesium ion binding, F:phospholipid-translocating ATPase activity, P:ATP catabolic process, P:ion transmembrane transport, P:phospholipid translocation, C:cytoplasmic vesicle membrane, C:integral to membrane, F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism, P:cation transport, P:phospholipid translocation, C:integral to membrane, F:hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances, F:phospholipid-translocating ATPase activity, P:cation transport
UniProtAlternative splicing, ATP-binding, Complete proteome, Cytoplasmic vesicle, Endoplasmic reticulum, Hydrolase, Magnesium, Membrane, Metal-binding, Nucleotide-binding, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp15042541Homo sapiens4kidneyglomeruliDiabetes (diabetic nephropathy)2.8< 0.01RNA microarray15042541
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.260.004RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.018792802LC-MS/MS24172336
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)4.920.001RNA microarray25770168
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.341.74E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium