CKDdb-logoCKDdb - Molecule ID A5824

geneAkr7a2, Afar2, Aiar
nameAflatoxin B1 aldehyde reductase member 2
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARK72_RATQ8CG45ENSRNOG00000017780171445Rn.8548603418

Functions and classifications

GOC:Golgi apparatus, C:Golgi stack, C:mitochondrion, F:alditol:NADP+ 1-oxidoreductase activity, F:aldo-keto reductase (NADP) activity
UniProtAcetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Golgi apparatus, NADP, Oxidoreductase, Reference proteome, Phosphoprotein
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)2.81< 0.05LC-MS/MS19845401
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.64 nLC-ESI-UHR-QToF-MS/MS23344851
Exp24497609Rattus norvegicus kidneyglomeruliPuromycin_induced (Puromycin nephropathy model)0.71< 0.05LC-MS/MS24497609
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)3.10.05LC-MS/MS24726496

Compile date 08-10-2018© iMODE-CKD consortium