CKDdb-logoCKDdb - Molecule ID A5823

geneAdprhl2
namePoly(ADP-ribose) glycohydrolase ARH3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARHL2_MOUSEQ8CG72ENSMUSG00000042558100206Mm.11285610624

Functions and classifications

GOC:mitochondrial matrix, C:nucleus, F:metal ion binding, F:poly(ADP-ribose) glycohydrolase activity, P:metabolic process, F:hydrolase activity
UniProt3D-structure, Complete proteome, Cytoplasm, Hydrolase, Magnesium, Metal-binding, Mitochondrion, Nucleus, Polymorphism, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.540.043478913LC-MS/MS24172336
Exp25769567Homo sapiens19kidneygraftsChronic_rejection (Chronic_rejection)0.36< 0.05ESI-TOF/TOF25769567
Exp25770168Homo sapiens17bloodmononuclear cellsGlomerulonephritis (IgA nephropathy)4.920.005RNA microarray25770168
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.260.007928RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium