CKDdb-logoCKDdb - Molecule ID A5819

geneAraf
nameSerine/threonine-protein kinase A-Raf
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARAF_MOUSEP04627ENSMUSG0000000112711836Mm.220946311010

Functions and classifications

GOC:mitochondrion, F:ATP binding, F:metal ion binding, F:protein serine/threonine kinase activity, F:receptor signaling protein activity, P:negative regulation of apoptotic process, P:positive regulation of peptidyl-serine phosphorylation, P:regulation of proteasomal ubiquitin-dependent protein catabolic process, P:regulation of TOR signaling, F:kinase activity, C:cytosol, P:intracellular signal transduction, C:intracellular
UniProt3D-structure, Alternative splicing, ATP-binding, Complete proteome, Kinase, Metal-binding, Nucleotide-binding, Phosphoprotein, Polymorphism, Proto-oncogene, Reference proteome, Serine/threonine-protein kinase, Transferase, Zinc, Zinc-finger
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)7.640.004547RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium