CKDdb-logoCKDdb - Molecule ID A5813

geneAOC3, VAP1
nameMembrane copper amine oxidase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AOC3_HUMANQ16853ENSG000001314718639Hs.198241603735

Functions and classifications

GOC:cell surface, C:cytoplasm, C:integral component of membrane, C:microvillus, C:plasma membrane, F:aliphatic-amine oxidase activity, F:aminoacetone:oxygen oxidoreductase(deaminating) activity, F:calcium ion binding, F:cation channel activity, F:copper ion binding, F:phenethylamine:oxygen oxidoreductase (deaminating) activity, F:primary amine oxidase activity, F:protein homodimerization activity, F:quinone binding, F:tryptamine:oxygen oxidoreductase (deaminating) activity, P:amine metabolic process, P:cell adhesion, P:inflammatory response, P:response to antibiotic, C:integral to membrane, F:oxidoreductase activity, P:negative regulation of primary amine oxidase activity
UniProt3D-structure, Calcium, Cell adhesion, Complete proteome, Copper, Direct protein sequencing, Disulfide bond, Glycoprotein, Membrane, Metal-binding, Oxidoreductase, Polymorphism, Reference proteome, Signal-anchor, TPQ, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19398767Homo sapiens20kidneybiopsy sectionFibrosis (Interstitial fibrosis and tubular atrophy)2.070.00110421RNA microarray19398767
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.000938RNA microarray19698090
Exp23760282aMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)0.360.032RNA microarray23760282

Compile date 08-10-2018© iMODE-CKD consortium