CKDdb-logoCKDdb - Molecule ID A580G

geneARHGDIG
nameRho GDP-dissociation inhibitor 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GDIR3_HUMANQ99819ENSG00000242173398Hs.647388602844

Functions and classifications

GOC:cytoplasmic membrane-bounded vesicle, C:cytosol, C:membrane, F:GTPase activator activity, F:Rho GDP-dissociation inhibitor activity, P:negative regulation of cell adhesion, P:positive regulation of GTPase activity, P:regulation of protein localization, P:regulation of small GTPase mediated signal transduction, P:Rho protein signal transduction, C:cytoplasm, P:regulation of catalytic activity
UniProtComplete proteome, Cytoplasm, GTPase activation, Reference proteome
PADBunknown

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.40.0462RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.31< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium