CKDdb-logoCKDdb - Molecule ID A5805

geneAmy2
namePancreatic alpha-amylase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMYP_MOUSEP00688ENSMUSG00000079850100043684Mm.275426104650

Functions and classifications

GOC:extracellular space, F:alpha-amylase activity, F:calcium ion binding, F:chloride ion binding, P:carbohydrate catabolic process, P:polysaccharide digestion, P:small molecule metabolic process, F:cation binding, F:hydrolase activity, acting on glycosyl bonds, P:carbohydrate metabolic process, F:catalytic activity, F:cation binding, P:carbohydrate metabolic process
UniProt3D-structure, Calcium, Carbohydrate metabolism, Chloride, Complete proteome, Disulfide bond, Glycoprotein, Glycosidase, Hydrolase, Metal-binding, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)0.02< 0.05MALDI-TOF-MS16372274
Exp16549904Mus musculus10urinewholeGlomerulonephritis (membranoproliferative glomerulonephritis model)1.32 nano-LC-MS/MS16549904
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)2< 0.05MALDI-TOF-TOF17021608
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.3 LC-MS/MS20543976
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)0.410hybrid quadrupole-TOF, LC-MS/MS22536212
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.70.00025LC-MS/MS23228063
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.32 nLC-ESI-UHR-QToF-MS/MS23344851
Exp23464927Homo sapiens10urine Fabry (12 months of ERT)1.35<0.05QTOF MS/MS23464927
Exp24096133aHomo sapiens10urine>10kDaDiabetes (type 1 diabetes without retinopathy or nephropathy)0 1DE, MALDI24096133
Exp24096133bHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy)0.5 1DE, MALDI24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)1000 1DE, MALDI24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy)1000 1DE, MALDI24096133
Exp24172336Mus musculus6kidneycortexAKI (AKI)2.390.008867947LC-MS/MS24172336
Exp24886809Mus musculus6pancreaswholeDiabetes (type 2 diabetes)0.55< 0.05MALDI-TOF24886809
Exp25578432aHomo sapiens60urinesupernatantDiabetes (type 2 diabetes without nephropathy)0.818E10-5LC-MS/MS25578432
Exp25578432bHomo sapiens42urinesupernatantDiabetes (type 2 diabetes with retinopathy)0.76E10-5LC-MS/MS25578432
Exp25578432cHomo sapiens51urinesupernatantDiabetes (diabetes with overt diabetic nephropathy)0.496.1x10-4LC-MS/MS25578432

Compile date 08-10-2018© iMODE-CKD consortium