CKDdb-logoCKDdb - Molecule ID A5803

geneAMY2B
nameAlpha-amylase 2B precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMY2B_HUMANP19961ENSP00000354610280Hs.484588104660

Functions and classifications

GOC:extracellular region, F:alpha-amylase activity, F:metal ion binding, P:carbohydrate metabolic process, P:digestion, F:catalytic activity, F:cation binding
UniProtCalcium, Carbohydrate metabolism, Chloride, Complete proteome, Direct protein sequencing, Disulfide bond, Glycosidase, Hydrolase, Metal-binding, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp25578432aHomo sapiens60urinesupernatantDiabetes (type 2 diabetes without nephropathy)0.846.4E10-4LC-MS/MS25578432
Exp25578432bHomo sapiens42urinesupernatantDiabetes (type 2 diabetes with retinopathy)0.696E10-5LC-MS/MS25578432
Exp25578432cHomo sapiens51urinesupernatantDiabetes (diabetes with overt diabetic nephropathy)0.53E10-3LC-MS/MS25578432
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)2.743.60E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium