CKDdb-logoCKDdb - Molecule ID A5802

geneAmy1
nameAlpha-amylase 1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMY1_MOUSEP00687ENSMUSG0000007426411722Mm.439727104700, 104701, 104702

Functions and classifications

GOC:extracellular space, F:alpha-amylase activity, F:amylase activity, F:metal ion binding, P:carbohydrate metabolic process, F:cation binding
UniProtCalcium, Carbohydrate metabolism, Chloride, Complete proteome, Disulfide bond, Glycosidase, Hydrolase, Metal-binding, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp16549904Mus musculus10urinewholeGlomerulonephritis (membranoproliferative glomerulonephritis model)1.29 nano-LC-MS/MS16549904
Exp17021608Rattus norvegicus12urineexosomeAKI (AKI)4< 0.05MALDI-TOF-TOF17021608
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)3.780.05RNA microarray17579666
Exp18440303Rattus norvegicus20urineglycoproteinsGlomerulonephritis (adriamycin nephropathy and Thy1.1 induced glomerulonephritis)0 LC-MS/MS18440303
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection)0.2 LC-MS/MS20543976
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)1.250hybrid quadrupole-TOF, LC-MS/MS22536212
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.470.02277LC-MS/MS23228063
Exp24096133aHomo sapiens10urine>10kDaDiabetes (type 1 diabetes without retinopathy or nephropathy)1000 1DE, MALDI24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy)0 1DE, MALDI24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy)0 1DE, MALDI24096133
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome)2.73.40E-05LC-MS25150443
Exp25578432aHomo sapiens60urinesupernatantDiabetes (type 2 diabetes without nephropathy)0.863.1E10-3LC-MS/MS25578432
Exp25578432bHomo sapiens42urinesupernatantDiabetes (type 2 diabetes with retinopathy)0.743E10-4LC-MS/MS25578432
Exp25578432cHomo sapiens51urinesupernatantDiabetes (diabetes with overt diabetic nephropathy)0.51.4E10-3LC-MS/MS25578432
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)8.011.89E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium