CKDdb-logoCKDdb - Molecule ID A5795

geneAMPD3
nameAdenosine monophosphate deaminase 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMPD3_HUMANQ01432ENSG00000133805272Hs.501890102772, 612874

Functions and classifications

GOC:cytosol, F:AMP deaminase activity, F:metal ion binding, P:AMP catabolic process, P:IMP salvage, P:purine nucleobase metabolic process, P:purine-containing compound salvage, P:IMP biosynthetic process
UniProtAlternative splicing, Complete proteome, Disease mutation, Hydrolase, Metal-binding, Nucleotide metabolism, Phosphoprotein, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17327501aMus musculus6kidneywholeIAKI (Ischemic acute kidney injury)5.54< 0.05RNA microarray17327501
Exp17327501bMus musculus6kidneywholeIAKI (Ischemic acute kidney injury)484.38< 0.05RNA microarray17327501
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.440.00942RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.451.28E-05NGS, RNA-seq.22266139

Compile date 08-10-2018© iMODE-CKD consortium