CKDdb-logoCKDdb - Molecule ID A5793

geneAMPD1
nameAdenosine monophosphate deaminase 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMPD1_HUMANP23109ENSG00000116748270Hs.89570102770, 615511

Functions and classifications

GOC:cytosol, F:AMP deaminase activity, F:metal ion binding, P:IMP salvage, P:purine nucleobase metabolic process, P:purine-containing compound salvage, P:response to organic substance, P:IMP biosynthetic process
UniProtAlternative splicing, Complete proteome, Disease mutation, Hydrolase, Metal-binding, Nucleotide metabolism, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.240.00224RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.090.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium