CKDdb-logoCKDdb - Molecule ID A5790

geneAMFR, RNF45
nameE3 ubiquitin-protein ligase AMFR
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AMFR_HUMANQ9UKV5ENSG00000159461267Hs.295137603243

Functions and classifications

GOC:dendrite, C:growth cone, C:integral component of endoplasmic reticulum membrane, C:neuronal cell body, C:nucleus, F:receptor activity, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:aging, P:cellular component movement, P:endoplasmic reticulum unfolded protein response, P:ER-associated ubiquitin-dependent protein catabolic process, P:learning or memory, P:protein oligomerization, P:protein polyubiquitination, C:cytoplasm, P:protein ubiquitination, C:integral to endoplasmic reticulum membrane, F:metal ion binding, P:ER-associated protein catabolic process
UniProt3D-structure, Complete proteome, Endoplasmic reticulum, Ligase, Membrane, Metal-binding, Phosphoprotein, Polymorphism, Receptor, Reference proteome, Transmembrane, Transmembrane helix, Ubl conjugation pathway, Zinc, Zinc-finger
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.370.0401429RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium