CKDdb-logoCKDdb - Molecule ID A5769

geneAldh9a1, ABALDH
name4-trimethylaminobutyraldehyde dehydrogenase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL9A1_MOUSEQ9JLJ2ENSMUSG0000002668756752Mm.330055602733

Functions and classifications

GOC:cytosol, C:mitochondrion, C:plasma membrane, F:4-trimethylammoniobutyraldehyde dehydrogenase activity, F:amine binding, F:aminobutyraldehyde dehydrogenase activity, F:NAD binding, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, P:carnitine biosynthetic process, P:carnitine metabolic process, P:cellular aldehyde metabolic process, P:kidney development, P:liver development, P:neurotransmitter biosynthetic process
UniProtAcetylation, Complete proteome, Cytoplasm, Direct protein sequencing, NAD, Oxidoreductase, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.490.01cDNA microarray19099603
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp21544065cRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)1.140.027MALDI-TOF/TOF21544065
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.48 nLC-ESI-UHR-QToF-MS/MS23344851
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)0.140.02LC-MS/MS24726496

Compile date 08-10-2018© iMODE-CKD consortium