CKDdb-logoCKDdb - Molecule ID A5762

geneALDH3A1, ALDH3
nameAldehyde dehydrogenase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AL3A1_HUMANP30838ENSG00000108602218Hs.531682100660

Functions and classifications

GOC:cytosol, C:endoplasmic reticulum, F:3-chloroallyl aldehyde dehydrogenase activity, F:alcohol dehydrogenase (NADP+) activity, F:aldehyde dehydrogenase (NAD) activity, F:aldehyde dehydrogenase [NAD(P)+] activity, P:aging, P:cellular aldehyde metabolic process, P:positive regulation of cell proliferation, P:response to cAMP, P:response to drug, P:response to glucocorticoid, P:response to hypoxia, P:response to nutrient, P:response to glucocorticoid stimulus
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, NAD, NADP, Oxidoreductase, Polymorphism, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19688726aRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)3.03 MALDI-TOF19688726
Exp19688726aRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)4.92 MALDI-TOF19688726
Exp19688726bRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)2.46 MALDI-TOF19688726
Exp19688726bRattus norvegicus kidneyinterstitial fibroblastFibrosis (TGFbeta in vitro model)2.83 MALDI-TOF19688726
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.240.0000374RNA microarray19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.295.43E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium