CKDdb-logoCKDdb - Molecule ID A5751

geneAKR1B10, AKR1B11
nameAldo-keto reductase family 1 member B10
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AK1BA_HUMANO60218ENSG0000019807457016Hs.116724604707

Functions and classifications

GOC:cytosol, C:extracellular region, C:lysosome, F:aldo-keto reductase (NADP) activity, F:geranylgeranyl reductase activity, F:indanol dehydrogenase activity, F:retinal dehydrogenase activity, P:cellular aldehyde metabolic process, P:daunorubicin metabolic process, P:digestion, P:doxorubicin metabolic process, P:farnesol catabolic process, P:phototransduction, visible light, P:retinoid metabolic process, P:steroid metabolic process, P:steroid metabolic process
UniProt3D-structure, Acetylation, Complete proteome, Lysosome, NADP, Oxidoreductase, Polymorphism, Reference proteome, Secreted
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.350.0201RNA microarray19698090
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.46< 0.05RNA-seq23757392
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.370.0000274RNA microarray24569379
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.210.014302RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium