CKDdb-logoCKDdb - Molecule ID A5749

geneAifm2, Amid
nameApoptosis-inducing factor 2
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AIFM2_MOUSEQ8BUE4ENSMUSG0000002008571361Hs.650680605159

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:lipid particle, C:mitochondrial outer membrane, C:mitochondrion, F:DNA binding, F:electron-transferring-flavoprotein dehydrogenase activity, F:flavin adenine dinucleotide binding, F:NADH dehydrogenase (ubiquinone) activity, P:apoptotic mitochondrial changes, P:chromosome condensation, P:execution phase of apoptosis, P:positive regulation of apoptotic process
UniProtAlternative splicing, Complete proteome, Cytoplasm, DNA-binding, FAD, Flavoprotein, Lipoprotein, Membrane, Mitochondrion, Mitochondrion outer membrane, Myristate, Oxidoreductase, Reference proteome, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17881425Mus musculus12urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)  MALDI-TOF-MS17881425
Exp18339188aHomo sapiens13bloodperipheral blood mononuclear cell (PBMC)Fabry (6 months of ERT) 0.05870468microarray18339188
Exp20134395Homo sapiens9urinewholeFibrosis (Interstitial fibrosis and tubular atrophy)25.990.042MALDI-TOF-MS, LTQ linear ion trap, capLC-ESI-ITMS/MS20134395
Exp23671862aMus musculus8heartsectionDiabetes (Diabetic Cardiomyopathy)2.58< 0.05micro-liquid chromatography system + LTQ Velos ion trap mass spectrometer23671862
Exp23671862bMus musculus8heartsectionDiabetes (Diabetic Cardiomyopathy)0.45< 0.05micro-liquid chromatography system + LTQ Velos ion trap mass spectrometer23671862

Compile date 08-10-2018© iMODE-CKD consortium