CKDdb-logoCKDdb - Molecule ID A5748

geneAgxt2, Agt2
nameAlanine--glyoxylate aminotransferase 2
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AGT2_RATQ64565ENSRNOG0000001782183784Rn.1874612471

Functions and classifications

GOC:mitochondrial matrix, F:(R)-3-amino-2-methylpropionate-pyruvate transaminase activity, F:alanine-glyoxylate transaminase activity, F:beta-alanine-pyruvate transaminase activity, F:pyridoxal phosphate binding, P:glycine biosynthetic process, by transamination of glyoxylate, P:glyoxylate catabolic process, P:L-alanine catabolic process, by transamination, P:positive regulation of nitric oxide biosynthetic process, C:mitochondrion, F:alanine-glyoxylate transaminase activity, F:pyridoxal phosphate binding, P:glycine biosynthetic process, by transamination of glyoxylate, P:glyoxylate catabolic process, P:L-alanine catabolic process, by transamination, P:positive regulation of nitric oxide biosynthetic process, F:pyridoxal phosphate binding, F:transaminase activity, P:metabolic process
UniProtAcetylation, Aminotransferase, Complete proteome, Direct protein sequencing, Mitochondrion, Pyridoxal phosphate, Reference proteome, Transferase, Transit peptide, ,
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20093355Homo sapiens33kidneyFibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp21544065aRattus norvegicus17kidneyDiabetes (diabetic nephropathy in T1D)3.130.003MALDI-TOF/TOF21544065

Compile date 08-10-2018© iMODE-CKD consortium