CKDdb-logoCKDdb - Molecule ID A5743

geneAfmid
nameKynurenine formamidase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
KFA_MOUSEQ8K4H1ENSMUSG0000001771871562Mm.273958

Functions and classifications

GOC:cytoplasm, C:cytosol, C:nucleus, F:arylformamidase activity, P:'de novo' NAD biosynthetic process from tryptophan, P:tryptophan catabolic process to kynurenine, F:hydrolase activity
UniProtAlternative splicing, Complete proteome, Cytoplasm, Direct protein sequencing, Hydrolase, Nucleus, Reference proteome, Tryptophan catabolism
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.480.01cDNA microarray19099603
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)2.973.85E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium