CKDdb-logoCKDdb - Molecule ID A5742

geneAFG3L2
nameAFG3-like protein 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFG32_HUMANQ9Y4W6ENSG0000014138510939Hs.726355604581, 610246, 614487

Functions and classifications

GOC:integral component of membrane, C:mitochondrial inner membrane, C:mitochondrion, F:ATP binding, F:metalloendopeptidase activity, F:nucleoside-triphosphatase activity, F:unfolded protein binding, F:zinc ion binding, P:axonogenesis, P:cell death, P:cristae formation, P:mitochondrial fusion, P:mitochondrial protein processing, P:muscle fiber development, P:myelination, P:nerve development, P:neuromuscular junction development, P:proteolysis, P:regulation of multicellular organism growth, P:righting reflex, P:death, C:integral to membrane, F:metal ion binding, P:protein catabolic process
UniProt3D-structure, ATP-binding, Complete proteome, Disease mutation, Hydrolase, Membrane, Metal-binding, Metalloprotease, Mitochondrion, Neurodegeneration, Nucleotide-binding, Protease, Reference proteome, Spinocerebellar ataxia, Transmembrane, Transmembrane helix, Zinc, Acetylation
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.070.0123RNA microarray19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.220.013755561LC-MS/MS24172336
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)40.016189503LC-MS/MS24316357

Compile date 08-10-2018© iMODE-CKD consortium