CKDdb-logoCKDdb - Molecule ID A5727

geneADH1B, ADH2
nameAlcohol dehydrogenase beta chain
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADH1B_HUMANP00325ENSG00000196616125Hs.4103720

Functions and classifications

GOC:cytosol, F:alcohol dehydrogenase activity, zinc-dependent, F:zinc ion binding, P:ethanol oxidation, P:xenobiotic metabolic process, F:oxidoreductase activity, F:metal ion binding, F:nucleotide binding
UniProt3D-structure, Acetylation, Complete proteome, Cytoplasm, Direct protein sequencing, Metal-binding, NAD, Oxidoreductase, Polymorphism, Reference proteome, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.250.00277RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.270.00347RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.370.0403RNA microarray19698090
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)up MS/MS, LTQ LX linear ion trap20093355
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)2.91< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)23.33< 0.05RNA microarray21752957
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)30.06< 0.05RNA microarray21752957
Exp22172726Homo sapiens20kidneyglomeruliDiabetes (type 2 diabetic nephropathy)1.450.0012QSTAR Elite LC-MS/MS22172726
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.280.0327812RNA microarray23935909
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.280.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium