CKDdb-logoCKDdb - Molecule ID A5721

geneCABC1, ADCK3, PP265
nameChaperone-activity of bc1 complex-like, mitochondrial precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADCK3_HUMANQ8NI60ENSP0000035573956997Hs.118241606980, 612016

Functions and classifications

GOC:mitochondrion, F:ATP binding, F:protein serine/threonine kinase activity, P:cell death, P:protein phosphorylation, P:ubiquinone biosynthetic process, C:mitochondrion, F:transferase activity, transferring phosphorus-containing groups, P:metabolic process, F:transferase activity, transferring phosphorus-containing groups, F:transferase activity, transferring phosphorus-containing groups, F:transferase activity, transferring phosphorus-containing groups
UniProtAlternative splicing, ATP-binding, Chaperone, Complete proteome, Disease mutation, Kinase, Mitochondrion, Neurodegeneration, Nucleotide-binding, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase, Transit peptide, Ubiquinone biosynthesis
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.873.23E-06RNA microarray20019191
Exp24927646aMus musculus16kidney Diabetes (diabetic nephropathy treated with Phlorizin)0.98< 0.05LC-MS/MS24927646
Exp24927646bMus musculus16kidney Diabetes (diabetic nephropathy)0.61< 0.05LC-MS/MS24927646

Compile date 08-10-2018© iMODE-CKD consortium