CKDdb-logoCKDdb - Molecule ID A5715

geneADAM30, UNQ2509/PRO5997, UNQ2509
nameADAM 30 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA30_HUMANQ9UKF2ENSG0000013424911085Hs.283011604779

Functions and classifications

GOC:integral component of membrane, C:plasma membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:binding of sperm to zona pellucida, P:multicellular organism reproduction, P:proteolysis, C:integral to membrane, F:metal ion binding
UniProtAlternative splicing, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.410.00586RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.35< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.049762673LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.261.10E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium