CKDdb-logoCKDdb - Molecule ID A5714

geneADAM28, ADAM23, MDCL
nameADAM 28 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ADA28_HUMANQ9UKQ2ENSG0000004298010863Hs.174030606188

Functions and classifications

GOC:extracellular region, C:integral component of membrane, C:plasma membrane, F:metalloendopeptidase activity, F:metallopeptidase activity, F:zinc ion binding, P:proteolysis, P:spermatogenesis, P:integrin-mediated signaling pathway, C:integral to membrane, F:metal ion binding
UniProtAlternative splicing, Cell membrane, Cleavage on pair of basic residues, Complete proteome, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Membrane, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen, Integrin
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.160.0000347RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.240.00038RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)4.51< 0.05RNA microarray21752957

Compile date 08-10-2018© iMODE-CKD consortium